How to Take Clomid for Infertility

How to Take Clomid for Infertility

Because it can cause dizziness or vision changes, you’ll want to avoid alcohol and marijuana, as these can exacerbate the symptoms. You’ll also want to avoid driving or operating machinery until you know how Clomid affects you. The most common of these are bloating and stomach or pelvic pain. Adding plans allows you to compare formulary status to other drugs in the same class. The combination of online prescription refills, easy access to our knowledgeable clinicians and savings opportunities enhance your treatment experience. Your doctor may order certain lab tests to check your body’s response to clomiphene.

  • It’s an injected drug that can prevent early ovulation in women who are having fertility procedures.
  • The ascorbic acid dominant genotype (AA) was found to be more responsive to antioxidant effect.
  • This is a condition in which your ovaries swell to several times their size, leaking fluid into your abdomen.
  • Researchers say Clomid has a multiple pregnancy rate of approximately 8-10%, though a 2021 study found it to be less than 3-4%.
  • Utilizing advanced tools and technologies, our doctors take on the toughest cases, providing renewed hope for would-be parents.
  • It does this by blocking estrogen from binding to its receptor.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Clomid only for the indication prescribed. Therapy is generally given over a period of several months. Talk to your doctor if you have concerns about the possible effects of Clomid on a new pregnancy.

Additional Treatments

The hormones that control reproduction are the same in men and women. Thus, men with infertility may take the same fertility drugs as women, to stimulate sperm production. Clomiphene triggers the brain’s pituitary gland to secrete an increased amount of follicle stimulating hormone (FSH) and LH (luteinizing hormone). This action stimulates the growth of the ovarian follicle and thus initiates ovulation. Clomiphene citrate is commonly indicated to treat patients diagnosed with anovulatory or oligo-ovulatory infertility to induce ovulation for patients wishing to conceive. It is also indicated for the treatment of male infertility to induce spermatogenesis.

  • The following information applies only to female patients taking clomiphene.
  • Therefore, the hypothalamus signals the pituitary to increase FSH production which stimulates ovarian follicular recruitment and growth leading to increased estrogen production.
  • Your doctor will likely instruct you to take Clomid at the beginning of your menstrual cycle, typically between days 3 and 5.
  • The results were restricted to articles written in English.
  • There doesn’t seem to be a difference in pregnancy success between beginning Clomid on day 3 or day 5.

Clomiphene must be taken by mouth exactly as directed by your doctor in order to be most effective.

Before taking this medicine

A recent study showed an increase in pregnancies when infertile males took a combination of Clomid and vitamin E when compared to placebo. The dose given can range from 12.5 to 400 milligrams (mg) per day. This doesn’t mean you should brush off the risk of having twins, only that you shouldn’t assume Clomid will get you twins.

  • This action stimulates the growth of the ovarian follicle and thus initiates ovulation.
  • You take it just like any other prescription medication – swallowed with a nice big chug of water.
  • Ovulation and pregnancy rates have been shown to be similar whether the drug is started on day two, three, four, or five.
  • If no cyst is present, Clomid treatment is given for five days.
  • The “Clomid Crazies” are a bit like PMS mood swings—but slightly worse.

Different doctors may have slightly different protocols for taking the medication. You may then label the calendar on the days you mayovulate (most likely days 12-15). You should have intercourse at least on days 12, 14, and 16 of your cycle. Then count and label your calendar on “days 27-31.” This may be when your period begins again. If your cycle has not begun by “day 31″ please call our office.

Triplets or quadruplets on are rare, happening less than 1% of the time. While having twins certainly brings many benefits, it’s important to note that twin pregnancies have higher risks of complications for both the expecting parent and the babies. More severe side effects of Clomid can include abnormal vaginal bleeding, mood changes, and vision changes.

Clomid Progress Checks

If you are feeling more nervous than excited, be reassured that it is normal. Pregnancy after infertility is not always easy, especially emotionally. Progesterone is a hormone that rises after ovulation, and testing for it can confirm whether or not Clomid triggered ovulation. Another reason for testing progesterone levels is to ensure levels are not too low.

These results were partly supported by Yilmaz et al. (2014). On the contrary, Ohnishi et al. (1986) found that CC induced genolethal DNA damages in the Escherichia coli PolA−/PolA+ with S9. Duran et al. (2006) reported that CC significantly and dose-dependently increased micronucleus frequency in bone marrow cells of rats. In a work of Yilmaz et al. (2014), CC genotoxicity was measured by bacterial and mammalian test systems. Coli TA97 and TA100 strains, however it significantly induced chromosomal aberrations, DNA damage and micronucleus in human peripheral blood lymphocytes. Authors further added an investigation published in 2015 regarding CC induced Sister Chromatid Exchange (SCE).


Your dosage depends on your health condition and response to therapy. Do not take it more often or longer than prescribed by your doctor. Prolonged treatment with this drug is not recommended and should not be more than 6 cycles. You may be asked to record your body temperature, perform ovulation tests, and time intercourse correctly for best results.

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